Thomas Thum,Johann Bauersachs,Stefan Engelhardt,Carina Gross
申请号：
US14947291
公开号：
US20160177302A1
申请日:
2015.11.20
申请国别(地区):
US
年份:
2016
代理人:
摘要：
In some embodiments, the invention is directed to a method for diagnosing fibrosis and/or fibrosis related diseases and to a method for screening a pharmaceutically active compound for the treatment of fibrosis and/or fibrosis related diseases. The present invention further relates to compositions for use in the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions modulate the activity of a miRNA for the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions inhibit the activity of miR-21 for the treatment, amelioration, and/or prevention of fibrosis.
