Daniel Paul Teufel,Catherine Lucy Stace,Silvia Pavan,Edward Walker,Leonardo Baldassarre
申请号：
US16838367
公开号：
US10792368B1
申请日:
2020.04.02
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of membrane type 1 metalloprotease (MT1-MMP). The invention also describes drug conjugates comprising said peptides, conjugated to one or more effector and/or functional groups which have utility in imaging and targeted cancer therapy.
