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Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic acid synthetic complex
专利权人:
Claudia Schwab;Moonhee Lee;Jian-Ping Guo;Patrick L. McGeer
发明人:
Patrick L. McGeer,Moonhee Lee,Jian-Ping Guo,Claudia Schwab
申请号:
US13195216
公开号:
US20130035388A1
申请日:
2011.08.01
申请国别(地区):
US
年份:
2013
代理人:
摘要:
This patent pertains to selective inhibition of assembly of the membrane attack complex of complement by use of less than 1 kDa molecular weight forms of the aurin tricarboxylic acid synthetic complex (ATAC), and their derivatives. It further pertains to the use of these materials to treat human conditions where there is evidence of self destruction of host tissue by the membrane attack complex. These diseases include, but are not limited to, Alzheimer disease, age related macular degeneration, and atherosclerosis.
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