A method for identifying an optimal image frame is presented. The method includes receiving a selection of an anatomical region of interest in an object of interest. Furthermore, the method includes obtaining a plurality of image frames corresponding to the selected anatomical region of interest. The method also includes determining a real-time indicator corresponding to the plurality of acquired image frames, wherein the real-time indicator is representative of quality of an image frame. In addition, the method includes communicating the real-time indicator to aid in selecting an optimal image frame. Systems and non-transitory computer readable medium configured to perform the method for identifying an optimal image frame are also presented.