Fischer, Roman,Kontermann, Roland,Pfizenmaier, Klaus,Siegemund, Martin
申请号:
AU2018247931
公开号:
AU2018247931A1
申请日:
2018.04.05
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to a tumor necrosis factor receptor (TNFR) binding protein complex comprising 12 or more protein ligands (PLs) that specifically bind to the extracellular part of the same TNFR. Preferably, the TNFR binding protein complex binds to the extracellular part of TNFR2. Preferably, the TNFR binding protein complex of the present invention further comprises two or more polymerization domains (PD).