UNIVERSITE BLAISE PASCAL-CLERMONT-FERRAND II;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
Jonathan Claude Alexandre LAO,Edouard Daniel Albert JALLOT,Xavier DIEUDONNE
申请号：
US15514724
公开号：
US20170348462A1
申请日:
2015.09.28
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates to an implant material for filling bone defects, for bone regeneration, and for bone tissue engineering, to an implant comprising said material, and to methods for manufacturing such an implant. The hybrid implant material according to the invention comprises: a biodegradable polymer P soluble in at least one solvent S1 and insoluble in at least one solvent S, different from the solvent S1； and a bioactive glass made of SiO2 and CaO and optionally containing P2O5 and/or optionally doped with strontium, characterized in that said implant includes a layering of a porous part having more than 90% by number of pores whose largest dimension is greater than or equal to 100 μm, and a dense part (2, 20, 200, 2000, 20000) having more than 80% by number of pores whose largest dimension is less than 50 μm. The invention is useful in the field of bone regeneration, particularly in the field of bone tissue engineering.
