Problem to be solved: to provide a pharmaceutical containing acetaminophen in a high content, and, in particular, to provide a compact tablet (ordinary tablet, slow release tablet) having excellent elution, hardness, and uniformity of the content of the drug, and a method for producing the same.The present invention is based on the preparation of acetaminophen having a predetermined particle diameter, and the method of manufacturing the same, and according to the present invention, by improving the fluidity of acetaminophen, it is possible to suppress the secondary agglomeration and to increase the manufacturing efficiency and to reduce the cost, thereby reducing the workability of miniaturization and the like It is very useful as good acetaminophen pharmaceutical and its manufacturing method.