Thiazole-based nitric oxide donors having aryl substituent(s) and uses thereof

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专利权人:

Peter Assaf

发明人:

Peter Assaf

申请号：

US12076828

公开号：

US08134010B2

申请日:

2008.03.24

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Disclosed are novel NO-donating compounds, designed such that when NO is released from the compound a residue which is a naturally occurring metabolite is formed, and thus a development of tolerance to the compounds upon repetitive administration is prevented or decreased. Also disclosed are methods of preparing such NO-donating compounds, pharmaceutical compositions and medical devices containing such compounds and methods utilizing such compounds in the treatment of various medical conditions.

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