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SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AS AGGRECANASE INHIBITORS FOR THE TREATMENT OF OSTEOARTHRITIS
专利权人:
MERCK PATENT GMBH
发明人:
Markus KLEIN,Sven LINDEMANN
申请号:
US14765913
公开号:
US20150368188A1
申请日:
2014.01.16
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to compounds of the formula I and in particular medicaments comprising at least one compound of the formula I for use in the treatment and/or prophylaxis of physiological and/or pathophysiological states in the triggering of which ADAMTS5 is involved, in particular for use in the treatment and/or prophylaxis of osteoarthritis, hepatocirrhosis, traumatic cartilage injuries, pain, allodynia or hyperalgesia.
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中国工程科技知识中心
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