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Vaccines Including Antigen From Four Strains of Influenza Virus
专利权人:
Theodore Tsai
发明人:
Theodore Tsai
申请号:
US14035668
公开号:
US20140178429A1
申请日:
2013.09.24
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Vaccines of the invention include at least four influenza virus strains. In some embodiments, the vaccines are produced in cell culture rather than in eggs. In some embodiments, the vaccines include an adjuvant. In some embodiments, the vaccines are not split or whole virion vaccines, but are live or purified glycoprotein vaccines. In some embodiments, the vaccines contain substantially the same mass of hemagglutinin (HA) for each of the influenza virus strains. In some embodiments, the four strains will include two influenza A virus strains and two influenza B virus strains (‘A-A-B-B’). In other embodiments, the four strains will include three influenza A virus strains and one influenza B virus strain (‘A-A-A-B’).
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