A entry and exit assist system for a vehicle has a mounting slot formed within a door of the vehicle. A wheelchair has a set of wheels and a seat coupled to the set of wheels, wherein the set of wheels are one of detachable from or foldable under the wheelchair. A supporting connector is coupled to the wheelchair. The supporting connector slides into and engages the mounting slot holding the wheelchair above a ground area when the set of wheels are one of detached from or folded under the wheelchair. A seatback is slideably mounted on a track in the vehicle. Closing the door with the supporting connector engaging the mounting slot and holding the wheelchair above a ground area positions the wheelchair in the vehicle. The seatback provides back support for a user of the wheelchair.