A cartridge for use in an aerosol-generating system, the cartridge comprising: a first compartment having a first air inlet and a first air outlet, the first compartment containing a nicotine source; and a second compartment having a second air inlet and a second air outlet, the second compartment containing an acid source; wherein the first compartment comprises a first air flow channel extending from the first air inlet, or the first air outlet, longitudinally along at least a portion of the first compartment, wherein the first air flow channel is adjacent to and in fluid communication with the nicotine source; or wherein the second compartment comprises a second air flow channel extending from the second air inlet, or the second air outlet, longitudinally along at least a portion of the second compartment, wherein the second air flow channel is adjacent to and in fluid communication with the acid source; or wherein the first compartment comprises a first air flow channel extending from the first air inlet, or the first air outlet, longitudinally along at least a portion of the first compartment, wherein the first air flow channel is adjacent to and in fluid communication with the nicotine source; and the second compartment comprises a second airflow channel extending from the second air inlet, or the second air outlet, longitudinally along at least a portion of the second compartment, wherein the second air flow channel is adjacent to and in fluid communication with the acid source.La présente invention concerne une cartouche à utiliser dans un système de génération d'aérosol, la cartouche comprenant : un premier compartiment ayant une première entrée d'air et une première sortie d'air, le premier compartiment contenant une source de nicotine ; et un second compartiment ayant une seconde entrée d'air et une seconde sortie d'air, le second compartiment contenant une source d'acide ; le premier compartiment comprenant un premier canal d'écoulement d'air s'étendant