composições e métodos para o tratamento de distúrbios do sistema nervoso central.

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专利权人:

SAGE THERAPEUTICS, INC.

发明人:

ALBERT JEAN ROBICHAUD,BOYD L. HARRISON,FRANCESCO G. SALITURO,GABRIEL MARTINEZ BOTELLA

申请号：

BR20171107902

公开号：

BR112017007902(A2)

申请日:

2015.10.16

申请国别(地区):

巴西

年份:

2018

代理人:

摘要：

Described herein are neuroactive steroids of the Formula (I): or a pharmaceutically acceptable salt thereof; wherein (II), A, R1, R2, R3a, R4a, R4b, R5, R7a, and R7b are as defined herein. Such compounds are envisioned, in certain embodiments, to behave as GABA modulators. The present invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of use and treatment, e.g., such for inducing sedation and/or anesthesia.

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