A system and method for directing vibrational oscillating sonic waves toward a target tissue in the body of a person, to thereby influence a phenotypic differentiation of the target tissue at a cellular level, requires the use of an epidermal or implantable patch. Mounted on the patch is a sonic generator for generating sonic energy that entrains cellular functions of the target tissue for a desired phenotypic response. Also included is a unit for titrating the target tissue to monitor for changes in an expression level of the target tissue resulting from phenotypic differentiation.
