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COMPOUNDS FOR USE AS IRON(III) MRI CONTRAST AGENTS
专利权人:
The Research Foundation for The State University of New York
发明人:
Janet R. MORROW,Eric M. SNYDER,Didar ASIK
申请号:
US16615024
公开号:
US20200079806A1
申请日:
2018.05.21
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macro-cyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
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中国工程科技知识中心
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