INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
发明人:
KOEHLER, KARL R.,LEE, JIYOON
申请号：
CA3002164
公开号：
CA3002164A1
申请日:
2016.10.21
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided herein are methods for directing differentiation of human pluripotent stem cells into a three-dimensional multilayered skin composition comprising an epidermal layer, a dermal layer, and a plurality of cells capable of forming a functional hair follicle. Also provided herein are three-dimensional, multilayered engineered skin compositions and methods of using the same for drug screening, for screening compounds for effects on hair growth, and for other applications.
