Composition comprising a uridine source, an omega-3 PUFA for improving coordination, balance, grip strength or fine motor skills. The invention is directed to a combination of a uridine source and an omega-3-polyunsaturated fatty acid having 18-24 carbon atoms for use in •—the prevention or treatment of a disturbance in coordination of limbs in a mammal •—the prevention or treatment of a disturbance in equilibrium in a mammal •—for use in the prevention or treatment of a disturbance in limb strength •—or use in the prevention or treatment of a disturbance in a motor skill in a mammal.