The X-ray phase-shift contrast imaging method and the system thereof are provided. The X-ray phase-shift contrast imaging method utilizes characteristic X-rays of high throughput irradiating at the target from different positions or with different focal lengthspositions so as to form different X-ray images. The X-ray images are compared to define the voxels and combined to obtain the 3-D X-ray image. By using X-ray phase-shift contrast for imaging the soft tissue, the level of the image contrast may be enhanced several orders of magnitude and the linear energy transfer of the high energy photon beam is greatly reduced. Hence, the radiation dose absorbed by the tissue may be greatly reduced.本發明提供一種X光相位差對比成像的方法及其系統。該X光相位對比成像的方法是利用高通量特性X射線以不同方位或焦距照射組織以產生不同的X光圖像資訊,之後再將不同的X光圖像資訊進行比較以定義立體像素而形成立體X光影像。利用X光相位差對比對軟組織成像,其影像對比度可增加數個量級並使所使用的高能光子束的線性能量轉移大幅減少,因而減少組織輻射劑量。S110、S120、S130‧‧‧步驟