Gregory Hinkle,Laura Sepp-Lorenzino,Vasant Jadhav,Martin Maier,Stuart Milstein,Muthiah Manoharan,Kallanthottathil G. Rajeev
申请号:
US15591532
公开号:
US10513703B2
申请日:
2017.05.10
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention relates to RNAi agents, e.g., double-stranded RNAi agents, targeting the hepatitis B virus (HBV) genome, and methods of using such RNAi agents to inhibit expression of one or more HBV genes and methods of treating subjects having an HBV infection and/or HBV-associated disorder, e.g., chronic hepatitis B infection.