A method of and composition for treating a patient having Mycobacterium avium complex (MAC) and in one embodiment Mycobacterium avium subspecies paratuberculosis (MAP) causing one or more diseases an embodiment of the method including administering to the patient an effective amount of one or more antibiotics and administering to the patient an effective amount of ultraviolet blood irradtiation (UVBI) treatments and an embodiment of the composition including an effective amount of one or more antibiotics and an effective amount of UVBI treated blood of the patient.