Dong Ho Kim;Kyeong Soo Kim;Jong Soo Woo;Yong II Kim;Taek Kwan Kwon;Jae Hyun Park
发明人:
Yong II Kim,Dong Ho Kim,Taek Kwan Kwon,Kyeong Soo Kim,Jae Hyun Park,Jong Soo Woo
申请号:
US14232433
公开号:
US20140170213A1
申请日:
2012.07.11
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed is a capsule formulation for preventing or treating allergic rhinitis and asthma, which comprises two separate layers of: (1) a Montelukast layer comprising montelukast or a pharmaceutically acceptable salt thereof; and (2) a Levocetirizine layer comprising levocetirizine or a pharmaceutically acceptable salt thereof; and a method for the preparation thereof. The capsule formulation according to the present invention can completely separate two active ingredients, thereby minimizing the reactivity between them and improving product stability against aging effects, and thus, can optimize the therapeutic effects.