ACTIVATION SPECIFIQUE D'UN LYMPHOCYTE REGULATEUR ET SON UTILISATION POUR LE TRAITEMENT DE L'ASTHME, D'UNE MALADIE ALLERGIQUE, D'UNE MALADIE AUTOIMMUNE, D'UN REJET DE GREFFE ET POUR UNE INDUCTION DE TOLERANCE
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
发明人:
申请号：
EP16166807.4
公开号：
EP3112866A1
申请日:
2008.01.30
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention relates to a Treg cell activator for regulatory (Treg) cell activation via interaction with a Treg cell epitope as set forth in SEQ ID NO:1 which is HIV-1 gp120, or HIV-1 gp120 derived fragments, peptides or polypeptides thereof comprising an amino acid sequence as set forth in SEQ ID NO.: 3, SEQ ID NO.: 4, SEQ ID NO.: 5, SEQ ID NO.: 6, SEQ ID NO.: 7, SEQ ID NO.: 8, SEQ ID NO.: 9, or SEQ ID NO.: 10for use in a method for the prevention or treatment of a disease, which is characterized in that its clinical picture is influenced positively by an increase of activated Treg cells in response to the Treg cell activator.
