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Anti-il-23p19 antibodies
专利权人:
Boehringer Ingelheim International GmbH
发明人:
Nabozny Gerald Henry,Galler Annette Bettina,Garidel Patrick,Loging William Troy,Padula Steven John,Schultz-Fademrecht Torsten,Wang Elaine Ee-Ling
申请号:
NZ70080213
公开号:
NZ700802A
申请日:
2013.04.25
申请国别(地区):
NZ
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition comprising an antibody, wherein the pharmaceutical composition comprises: 70 to 100 mg/ml of the antibody and further comprises 100 to 300 mM sorbitol, wherein the pH of said pharmaceutical composition is in the range of pH 5.5 to 6.5, wherein the antibody is an anti-IL-23p19 antibody comprising a light chain comprising the amino acid sequence of SEQ ID NO:174 or 180 and a heavy chain comprising the amino acid sequence of SEQ ID NO:176 or 178. The present invention also relates to the use of such compositions for the manufacture of medicaments for treating patients for conditions selected from psoriasis, inflammatory bowel disease, psoriatic arthritis, multiple sclerosis, rheumatoid arthritis, spondyloarthritis, discoid lupus, malaria, malignant melanoma, aplastic anaemia, Huntington’s Disease, palmoplantar pustulosis, IgA nephritis, ANCA-Associated Vasculitis, scleritis, sepsis, COPD (chronic obstructive pulmonary disease) or asthma.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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