RENSSELAER POLYTECHNIC INSTITUTE;GENERAL ELECTRIC COMPANY
发明人:
Robert John Filkins,Ahmad Nadeem Ishaque,Alok Mani Srivastava,Peter William Lorraine,Holly Ann Camanzo,Xiaolei Shi,Vasile Bogdan Neculaes,Sam Joseph Camardello,Gregory Boverman,Ge Wang,Wenxiang Cong
申请号:
US14789585
公开号:
US20170000438A1
申请日:
2015.07.01
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present approach generally relates to systems and methods for implementing energy modulated tomographic imaging of nanoparticles. In certain embodiments, a first energy is used to activate probe particles labeling an anatomy or tissue of interest. The probe particles, once activated, emit photons at a different rate and/or spectrum in response to an underlying physiological event, such as action potentials propagating in the labeled anatomy or tissue. The emitted photons may then be detected and used to map or image the occurrence of the physiological event.