SAKSENA ANIL K.,GIRIJAVALLABHAN VIYYOOR MOOPIL,LOVEY RAYMOND G.,JAO EDWIN E.,BENNETT FRANK,MCCORMICK JINPING L.,WANG HAIYAN,PIKE RUSSELL E.,BOGEN STEPHANE L.,CHAN TIN YAU,LIU YI-TSUNG,ZHU ZHAONING,NJO
申请号:
CZ2003151
公开号:
CZ303213B6
申请日:
2001.07.19
申请国别(地区):
CZ
年份:
2012
代理人:
摘要:
Sloucenina (boceprevir) s inhibicní aktivitou na proteázu viru hepatitidy C (HCV), a zpusob prípravy této slouceniny. Farmaceutické prostredky s obsahem této slouceniny jsou použitelné pro lécení infekce virem hepatitidy C.In the present invention, there are disclosed novel compounds, which have hepatitis C virus (HCV) polypeptide protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.