САММАР Маршал Л. (US),БАР Фридерик Е. (US),ФАЙК Кэндис Д. (US),ЭСЧНЕР Джуди Л. (US)
申请号：
RU2010132581/15
公开号：
RU2010132581A
申请日:
2009.02.02
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A method of treating bronchopulmonary dysplasia, comprising administering an effective amount of a nitric oxide precursor to a patient in need of treatment. ! 2. The method according to claim 1, in which the nitric oxide precursor is selected from the group consisting of citrulline, a precursor that generates citrulline in vivo, arginine, a precursor that generates arginine in vivo, and combinations thereof. ! 3. The method according to claim 1, in which the appointment includes the appointment of oral, intravenous and combinations thereof. ! 4. The method according to claim 1, in which the patient is a newborn baby. ! 5. The method according to claim 4, in which the newborn baby is premature. ! 6. The method according to claim 1, in which the precursor of nitric oxide is administered in a dose in the range from about 100 mg to about 30,000 mg. ! 7. The method according to claim 6, in which the nitric oxide precursor is prescribed in a dose in the range from about 250 mg to about 1000 mg. ! 8. The method according to claim 1, in which the patient suffers from hypocytrullinemia, which is characterized by plasma citrulline levels of ≤37 μmol / L. ! 9. A method of treating chronic hypoxia of pulmonary hypertension, the method comprising administering an effective amount of a nitric oxide precursor to a patient in need of treatment. ! 10. The method according to claim 9, in which the nitric oxide precursor is selected from the group consisting of citrulline, a precursor that generates citrulline in vivo, arginine, a precursor that generates arginine in vivo, and combinations thereof. ! 11. The method according to claim 9, in which the appointment includes the appointment of oral, intravenous and combinations thereof. ! 12. The method according to claim 9, in which the patient is a newborn baby. ! 13. The method according to claim 11. Способ лечения бронхопульмонарной дисплазии, включающий назначение эффективного количества прекурсора окиси азота пациенту, который нуж
