A kind of prosthese for repairing hernia includes adhesion-resistant biodegradable region and opposite tissue ingrowth biodegradable region. When the prosthese is implanted patient, adhesion-resistant biodegradable region covers the fascia tissue defect of the hernia, is the hypodermis layer for being exposed substantially only to the host simultaneously positioned at above-mentioned adhesion-resistant biodegradable region with tissue ingrowth biodegradable region. This orientation permission tissue ingrowth biodegradable region is firmly incorporated the bodily tissue of host. The adhesion-resistant biodegradable region is towards internal organ and reduces the occurrence rate of adhesion and/or intestinal obstruction.