IMPROVED PHARMACEUTICAL COMPOSITION CONTAINING DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST AND METHOD FOR THE PREPARATION THEREOF

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专利权人:

RECORDATI IRELAND LIMITED;PHARMATHEN SA

发明人:

KARAVAS, EVANGELOS,KOUTRIS, MAKIS,SAMARA, VICKY,MATSINGOU, CHRISTINA,ILIOPOULOU, ATHINA

申请号：

MYPI 2010000318

公开号：

MY153857A

申请日:

2008.07.23

申请国别(地区):

MY

年份:

2015

代理人:

摘要：

THE PRESENT INVENTION RELATES TO THE FORMULATION OF SOLID DOSAGE FORMS COMPRISING A THERAPEUTICALLY EFFECTIVE AMOUNT OF A DIHYDROPYRIDINE CALCIUM CHANNEL ANTAGONIST SUCH AS LERCANIDIPINE OR SALT THEREOF, IN COMBINATION WITH COLLOIDAL SILICON DIOXIDE SUCH AS AEROSIL™ TO ENHANCE BIOAVAILABILITY AND IMPROVE SOLUBILITY, AND A PROCESS FOR THE PREPARATION THEREOF BY WET GRANULATION. THE MOST ILLUSTRATIVE DRAWING IS FIGURE 14

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http://www.ckcest.cn/home/