Robert L. Hudkins;Ming Tao;Thomas R. Bailey;Kurt A. Josef;Greg A. Hostetler;Sankar Chatterjee;Derek D. Dunn;Nadine C. Becknell;Lars J. S. Knutsen;Allison L. Zulli;Edward R. Bacon
发明人:
Edward R. Bacon,Thomas R. Bailey,Nadine C. Becknell,Sankar Chatterjee,Derek D. Dunn,Greg A. Hostetler,Robert L. Hudkins,Kurt A. Josef,Lars J. S. Knutsen,Ming Tao,Allison L. Zulli
申请号:
US13197243
公开号:
US08673916B2
申请日:
2011.08.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention is directed to methods of treating disorders mediated by Histamine H3 receptors by administering novel pyridazinone derivatives. In particular, the pyridazinone compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition/cognitive disorders.