Marinus, Jacobus VERWIJS,Radhika KARKARE,Michael, Douglas MOORE
申请号:
HK16100724.5
公开号:
HK1212632A
申请日:
2016.01.22
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
Pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of, or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of manufacturing, methods of administering, and kits thereof are disclosed.