1-ethyl-7-methyl-3-{4-[(3-methyl-3-pyridan-2-il) oxygen] phenyl}-1, 3-dihydro-2h-imidazo [4, 5-b] piridin-2-ona, phosphoric acid-10a inhibitors； drug synthesis containing the substance； and use for the prevention or treatment of schizophrenia.
The present invention relates to a crystal of 1-ethyl-7-methyl-3-{4-[(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)oxy]phenyl}-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one useful as a prophylactic or therapeutic agent for schizophrenia and the like, which shows an X-ray powder diffraction pattern having characteristic peaks at interplaner spacings (d) of 13.59 plus or minus 0.2 and 6.76 plus or minus 0.2 Angstroms in powder X-ray diffraction.FORMA CRISTALINA DE 1-ETIL-7-METIL-3-{4-[(3-METIL-3H-IMIDAZO[4,5-B]PIRIDIN-2-IL)OXI]FENIL}-1,3-DIHIDRO-2H-IMIDAZO[4,5-B]PIRIDIN-2-ONA, INHIBIDOR DE LA FOSFODIESTERASA 10A； COMPOSICION FARMACEUTICA QUE LA COMPRENDE； Y SU USO PARA LA PROFILAXIS O EL TRATAMIENTO DE LA ESQUIZOFRENIA.
