Disclosed is a sterilizable flexible surgical instrument system, comprising a flexible continuous body structure. The flexible continuous body structure comprises a distal structural body (11), a middle connecting body (15) and a proximal structural body (16). The distal structural body (11) comprises at least one distal structural segment (12, 13), the distal structural segments (12, 13) comprising a distal spacing disk (121, 131), a distal fixing disk (122, 132) and a structural backbone (123, 133). The proximal structural body (16) comprises the same number of proximal structural segments (17, 18) as distal structural segments (12, 13), the proximal structural segments (17, 18) comprising a proximal spacing disk (171, 181), a proximal fixing disk (172, 182) and a structural backbone (173, 183). The proximal structural segment (17, 18) is linked to the distal structural segment (12, 13) via a middle connecting body (15). A transmission unit (21) is further comprised. The transmission unit (21) comprises a transmission mechanism fixing plate (24) arranged in front of the middle connecting body (15). A gear transmission mechanism (22) for converting a rotary motion input into a linear motion output is arranged on the transmission mechanism fixing plate (24). An output end of the gear transmission mechanism (22) is securely connected to one end of a driving backbone (211) via a adaptor (23), and the other end of the driving backbone (211) passes through the proximal spacing disks (171, 181), and is then securely connected to the proximal fixing disks (172, 182).