John C. Amedio, JR.,Barbara Wallner,Marsha G. Marande
申请号：
US13796628
公开号：
US20140004192A1
申请日:
2013.03.12
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to pharmaceutical formulations that increase the solubility and bioavailability of indibulin, such as a spray-dried solid dispersion of indibulin with at least one matrix polymer. The invention further provides dosage formulations comprising the dispersion and processes for making the dispersion. The present invention also discloses a method of treating immune system based disorders, hyper-proliferative disorders, angiogenesis, malignancies, and neoplasms with the indibulin formulations disclosed herein.
