The present invention relates to a method for the treatment or prevention of atrial fibrillation and/or atrial flutter comprising coadministration of a therapeutically effective amount or less of dronedarone or a pharmaceutically acceptable salt thereof and a therapeutically effective amount or less of ranolazine or a pharmaceutically acceptable salt thereof. Also provided are methods for modulating ventricular and atrial rhythm and rate. This invention also relates to pharmaceutical formulations that are suitable for such combined administration.本發明關於一種供治療或預防心房纖維性顫動及/或心房撲動之方法,該方法包含共投予治療有效量或較少量之決奈達隆(dronedarone)或彼之醫藥上可接受之鹽與治療有效量或較少量之雷諾嗪(ranolazine)或彼之醫藥上可接受之鹽。本發明亦提供用於調節心室及心房之節律及速度之方法。本發明亦關於適合用於該組合投予之醫藥調製劑。
