DONNA STEUERWALD DUNYAK,DOUGLAS STEVEN PEARCE,GREGORY PAUL NITZEL,JACQUELINE GAYLE MARX,JAMES RICHARD THOMPSON,JAY GREGORY CALVERT,MIRA IVANOVA STOEVA,NANCEE LOIS OIEN,ROBERT GERARD ANKENBAUER
申请号：
BRPI0920248
公开号：
BRPI0920248A2
申请日:
2009.10.16
申请国别(地区):
BR
年份:
2016
代理人:
摘要：
The present invention is directed to novel nucleotide and amino acid sequences of Torque teno virus (&ldquo；TTV&rdquo；), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine TTV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include vaccines that provide TTV ORF1 protein, or peptide fragments thereof, as antigen.
