PROCÉDÉ DE PRODUCTION DE POLY(ACIDE AMINÉ)

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专利权人:

Takeda Pharmaceutical Company Limited

发明人:

申请号：

EP14818491.4

公开号：

EP3015488A1

申请日:

2014.06.25

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The present invention relates to a graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof (e.g., a graft copolymer (γ-PGA-PAE) of poly(γ-glutamic acid) (γ-PGA) and phenylalanine ethyl ester (PAE)), an ionized graft copolymer of a poly(amino acid) or a salt thereof and a hydrophobic primary amine compound or a salt thereof, nanoparticles containing the ionized graft copolymer, and a production method thereof. The nanoparticles acquired in this way are useful as an adjuvant for producing a vaccine.

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