Thomas C. Malone;Sougato Boral;Shimiao Wang;Xialing Guo;Julie A. Wurster
发明人:
Sougato Boral,Xialing Guo,Shimiao Wang,Julie A. Wurster,Thomas C. Malone
申请号：
US13150543
公开号：
US08455535B2
申请日:
2011.06.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides a compound represented by the formula:wherein ring systems A and B, and the variables R1, b, R6, Y, Z, X, R and a are defined in the specification. The compounds of the present invention may be used in a method for treating diseases related to unregulated tyrosine kinase signal transduction, such as cancer, blood vessel proliferative disorders, fibrotic disorders, mesangial cell proliferative disorders, and metabolic diseases.
