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METHOD AND COMPOSITION FOR ENHANCING TARGET CELLS UPTAKE OF THERAPEUTIC AGENTS
专利权人:
TSINGHUA UNIVERSITY
发明人:
LUO, YONGZHANG,CHEN, YANG,FU, YAN,JIA, LIN,CHANG, GUODONG
申请号:
EP12765089
公开号:
EP2702997A4
申请日:
2012.03.28
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention relates to a new use of a known medicament. Specifically, the invention relates to methods and compositions for enhancing the therapeutic efficacy of a therapeutic agent by increasing the uptake of the therapeutic agent by target cells, and in particular relates to a pharmaceutical composition comprising a regulating agent of lipid raft/caveolae-dependent endocytic pathway and some therapeutic agents, such as anti-tumor agents. The invention also relates to a method for screening a regulating agent of lipid raft/caveolae-dependent endocytic pathway capable of enhancing the therapeutic efficacy of anti-tumor agents.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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