Dustin McMinn,Henry Johnson,Simeon Bowers,David C. Moebius
申请号:
US15251688
公开号:
US10647744B2
申请日:
2016.08.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are tripeptide epoxy ketone protease inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula (X):and pharmaceutically acceptable salts and compositions including the same. The compounds and compositions provided herein may be used, for example, in the treatment of diseases including inflammation and neurodegenerative disease.