MOYENS ET METHODES POUR TRAITER UNE INFECTION PAR LE VIRUS DE L'HERPES

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专利权人:

HELMHOLTZ ZENTRUM MUENCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT (GMBH)

发明人:

HAMMERSCHMIDT, WOLFGANG,ZEIDLER, REINHARD,PICH, DAGMAR

申请号：

CA3009115

公开号：

CA3009115A1

申请日:

2017.02.28

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

The present invention provides herpesviruses, such as EBV, which lack at least one viral miRNA. Such herpesviruses lacking at least one viral miRNA are advantageously not capable of packaging their genome into the capsid, thereby producing HVLPs, which are substantially free of their herpesvirus genome or the nucleic acid molecule encoding the proteinaceous part of the HVLP and viral miRNA. Such HVLPs may be used as vaccine.

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