Provided are: a method for producing an aqueous ophthalmic composition, the method including the wet grinding of a mixture containing a carbonic anhydrase inhibitor, a cellulose derivative, and water, wherein the viscosity of a 2 mass% aqueous solution of the cellulose derivative at 20°C is 60 mPa∙s or less; and an aqueous ophthalmic composition containing a carbonic anhydrase inhibitor, a cellulose derivative, and water, wherein the absorbance of the aqueous ophthalmic composition with an optical path length of 1 mm at a wavelength of 600 nm is 1.1 or less, and the viscosity of a 2 mass% aqueous solution of the cellulose derivative at 20°C is 60 mPa∙s or less.