LEE KYEONG,WON MI SUN,KIM HWAN MOOK,PARK SONG KYU,LEE KI HO,LEE CHANG WOO,KIM BO KYUNG,BAN HYUN SEUNG,CHUNG KYUNG SOOK,RAVI NAIK
申请号：
IN2352/CHENP/2014
公开号：
IN2014CN02352A
申请日:
2014.03.27
申请国别(地区):
IN
年份:
2014
代理人:
摘要：
The present invention relates to novel compounds as HIF 1a inhibitors manufacturing process thereof and a pharmaceutical compositions. The compounds according to the present invention having inhibition activity against HIF 1a can be used as a therapeutic prevention and/or treatment for various solid cancers such as colon cancer liver cancer stomach cancer and breast cancer. Also the compounds according to the present invention are useful in the treatment of diabetic retinopathy and rheumatoid arthritis which are aggravated by HIF 1a mediated VEGFA expression.
