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Decreasing potential iatrogenic risks associated with influenza vaccines
专利权人:
Novartis AG
发明人:
Jens-Peter Gregersen
申请号:
US15150214
公开号:
US10155932B2
申请日:
2016.05.09
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Influenza viruses for use in preparing human vaccines have traditionally been grown on embryonated hen eggs, although more modern techniques grow the virus in mammalian cell culture e.g. on Vero, MDCK or PER.C6 cell lines. The inventor has realised that the conditions used for influenza virus culture can increase the risk that pathogens other than influenza virus may grow in the cell lines and have identified specific contamination risks. Suitable tests can thus be performed during manufacture in order to ensure safety and avoid iatrogenic infections.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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