The present invention relates to a barrier membrane arrangement for a medical device for providing a substantially liquid tight seal between a piercing member and a barrier member and a method for manufacturing such a barrier member arrangement. The present invention also relates to a method for connecting a first and a second medical device at the barrier member arrangement. The barrier member arrangement comprises a first member, a second member and a barrier member. The second member can be interlocked to the first member by means of a connection arrangement at an optional stage by a user. After interlocking the second member to the first member, the barrier member has been compressed to provide for an increased leakage security. The barrier member arrangement also provides for a prolonged working life of the barrier member and any medical device which comprises such a barrier member arrangement.