Commissariat à l'Énergie Atomique et aux Énergies Alternatives
发明人:
Pierre Jallon
申请号：
US16334825
公开号：
US20190298918A1
申请日:
2017.09.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
An automated system of regulation of a patient's blood sugar, including: a blood sugar sensor； an insulin injection device； and a processing and control unit capable of predicting the future evolution of the patient's blood sugar from a physiological model and of controlling the insulin injection device by taking the prediction into account, wherein: the physiological model includes a differential equation system describing the time variation of a plurality of state variables； and the processing and control unit is capable of implementing a step of automatic calibration of the physiological model including a step of estimation of initial values of the state variables by minimization of a quantity representative of the error, during a past observation period, between the blood sugar estimated based on the physiological model and the blood sugar measured by the sensor.
