A method for performing ambulatory electrocardiographic monitoring is provided. An ambulatory ECG monitor (11), that includes a plurality of sensing electrodes (48) coupled to self-powered sensing circuitry (71), is provisioned. A monitoring site (15) is located on the surface of a patients chest at midline and above the body of the sternum adjacent to the fourth and fifth intercostal spaces. The electrodes (48) are aligned and placed along the midline. The ambulatory ECG monitor (11) is removably adhered to the monitoring site (15) for the duration of monitoring. ECG data is sensed through the sensing electrodes (48) at the monitoring site (15) and the sensed ECG data is recorded into the sensing circuitry (71).
