ANDREA GIORI,GIACOMO MOMBELLI,SABRINA ARPINI,MARIO ACERBI
申请号：
BRPI1016023
公开号：
BRPI1016023A2
申请日:
2010.03.31
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
Process for removing pesticides from Ginkgo biloba extracts, which involves submitting an extract obtained by conventional methods to the following steps: a. Liquid-liquid extraction of the extract to obtain a medium polarity fraction containing ginkgo terpenes and pesticides not removable with hexane, and a high polarity fraction containing ginkgo flavone glycosides； b. crystallisation from the medium polarity fraction obtained at step a) to give an intermediate with a ginkgolide content of not less than 50%； c. crystallisation from the residual solution obtained at step b) to give an intermediate with a bilobalide content of not less than 50%； d. mixing of the high polarity fraction obtained at step a) with the ginkgo terpene intermediate and the bilobalide intermediate obtained at steps b) and c).
