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NOVEL PIPERAZINE ANALOGS AS BROAD SPECTRUM INFLUENZA ANTIVIRALS
专利权人:
发明人:
CIANCI CHRISTOPHER W,GERRITZ SAMUEL,LI GUO,PEARCE BRADLEY C,PENDRI ANNAPURNA,SHI SHUHAO,ZHAI WEIXU,ZHU SHIRONG
申请号:
IN2168/CHENP/2013
公开号:
IN2013CN02168A
申请日:
2013.03.19
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
32222316361111636A compound of Formula (I) is set forth including pharmaceutically acceptable salts thereof wherein Het is a 5 or 6 membered heterocycle with N O or S adjacent to the Ar substituent or adjacent to the point of attachment for the Ar substituent Ar is aryl or heteroaryl R is CH CHF or CH=CH W is NO Cl Br CHO CH=CH or CN X is Cl CH or CN Y is CH or N and Z is C C alkyl C C cycloalkyl substituted aryl substituted heteroaryl OR or NHR wherein R is selected from the group of H aryl heteroaryl C C alkyl and C C cycloalkyl. This compound is useful in compositions for the prevention and treatment of influenza virus.
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