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T-CELL RECEPTOR
专利权人:
Max Topp;Hans Stauss;Shao-An Xue
发明人:
Hans Stauss,Shao-An Xue,Max Topp
申请号:
US13498561
公开号:
US20120244132A1
申请日:
2010.09.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a T-cell receptor (TCR) which binds to a peptide from latent membrane protein 2 (LMP-2) from the Epstein Barr Virus (EBV) having the amino acid sequence CLGGLLTMV (SEQ ID No. 1) when presented by a major histocampatability complex (MHC) molecule. The present invention also provides a nucleotide sequence encoding such a TCR, a vector comprising such a nucleotide sequence and its use to produce a EBV-specific T-cell. The present invention also provides the use of EBV-specific T-cell for cellular immunotherapy.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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