Mutant OPAA enzymes with increased catalytic efficiency on organophosphorus compound EA1356

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专利权人:

发明人:

Steven P Harvey,Mark A Guelta,Leslie R McMahon

申请号：

US15896833

公开号：

US10124043B1

申请日:

2018.02.14

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention comprises isolated, mutant, non-wild-type organophosphorus acid anhydrolase (OPAA) enzymes having three site mutations, methods of production, and methods of use to effectively degrade organophosphorus compound EA1356 (2-methylcyclohexyl methylphosphonofluoridate) with greater catalytic efficiency than the wild-type OPAA enzyme.

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